Aligned electrospun nanofibers specify the direction of dorsal root ganglia neurite growth
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چکیده
منابع مشابه
Aligned electrospun nanofibers specify the direction of dorsal root ganglia neurite growth.
Nerve injury, a significant cause of disability, may be treated more effectively using nerve guidance channels containing longitudinally aligned fibers. Aligned, electrospun nanofibers direct the neurite growth of immortalized neural stem cells, demonstrating potential for directing regenerating neurites. However, no study of neurite guidance on these fibers has yet been performed with primary ...
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Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of postnatal-but not embryonic-mouse dorsal root ganglion cells in vitro, despite the fact that its receptors are expressed at both ages. To understand this difference, we have performed an oligonucleotide microarray experiment. We found that several hundred genes were regulated between embryonic and postnatal stages, and ...
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Electrospun nanofibers can be readily assembled into various types of scaffolds for applications in neural tissue engineering. The objective of this study is to examine and understand the unique patterns of neurite outgrowth from primary dorsal root ganglia (DRG) cultured on scaffolds of electrospun nanofibers having different orders, structures, and surface properties. We found that the neurit...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part A
سال: 2007
ISSN: 1549-3296,1552-4965
DOI: 10.1002/jbm.a.31285